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It also has been found to be incompatible with aminophylline, amobarbital sodium, aztreonam, chloramphenicol sodium succinate, chlorothiazide sodium, dexamethasone sodium phosphate, heparin sodium, methicillin sodium, pentobarbital sodium, phenobarbital sodium, secobarbital sodium, and sodium bicarbonate. Chloramphenicol diffuses readily into milk, pleural and ascetic fluids and crosses the placenta. Keep Chloramphenicol out of the reach of children and away from pets. A small fraction of this is in the form of unchanged chloramphenicol. Because of reported systemic toxicity, some USP medical experts recommend that ophthalmic chloramphenicol be reserved for serious ocular infections in which the etiologic organisms are resistant to all other ophthalmic antibiotics or for infections in which less toxic antibiotics are ineffective. Mantenga chloramphenicol/polymyxin B e hydrocortisone oftálmico a temperatura ambiente fuera del calor y de la humedad.

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